Previously, epidemiological studies have reported that high levels of homocysteine are associated with suspected or confirmed dementia.
The potential role of B-vitamins to support brain health is based on its ability to reduce levels of homocysteine, an amino acid linked to wasting in the brain, or atrophy. FDA concludes that there is little scientific evidence supporting this claim.” 4. In the US, the FDA permits a qualified health claim for PS relating to benefitting dementia/cognitive dysfuntion in the elderly, but with the qualification: “Very limited and preliminary scientific research suggests that phosphatidylserine may reduce the risk of dementia/cognitive dysfuntion in the elderly. The nutrient has a variety of unique regulatory and structural functions, including modulating the activity of receptors, enzymes, ion channels and signaling molecules. PS is a naturally occurring phospholipid found in organs with high metabolic activity, such as the brain, lungs, heart, liver and skeletal muscle. PhosphatidylSerine (PS)įollowing on from the omega-3s, there’s a good deal of evidence to support the role of PhosphatidylSerine (PS) during early brain development, and the lack of it during mental deterioration. Interest has focused on several different endpoints, including improving mood and reducing suicide rates among serving and ex-military personnel, speeding recovery from traumatic brain injury, and improving reaction times of fighter pilots.
Indeed, military interest in omega-3 is nothing new, with the November 2014 edition of Military Medicine focusing on the fatty acids as “nutritional armor”. Such findings are of obvious interest to the current and former members of the armed forces. According to data published in the Journal of Affective Disorders, increased levels of EPA+DHA (docosahexaenoic acid), EPA only, and the ratio of EPA to the omega-6 arachidonic acid (AA) were all associated with low PTSD severity symptoms in patients receiving omega-3 supplements at 3 months. Researchers have also reported a potential role for EPA in lowering the severity of symptoms of post-traumatic stress disorder (PTSD). In terms of mood, several studies, such as the French study published in the American Journal of Clinical Nutrition, have reported benefits for EPA and symptoms of depression. Several studies have reported that supplementation with EPA and DHA may result in improvements in behavior and learning of children, although such studies have their critics.
Linked to cognitive performance are reports that supplements of the fatty acids may improve mood and behavior. Results of a meta-analysis of 15 gold standard randomized controlled trials presented at the Experimental Biology 2016 event in San Diego, CA by scientists from Tufts University and Harvard indicated that EPA+DHA supplementation during pregnancy or infancy was associated with improved motor skills in the children (The FASEB Journal). The data linking marine omega-3 fatty acids and cognitive function has not always been consistent in this area, with experts noting that some studies have been performed in diseased patients (for example, Alzheimer’s disease) or have used insufficient doses.ĭespite these limitations, many clinical trials have shown clear benefits to cognitive health, with a 2015 meta-analysis of randomized, controlled trials showing that daily DHA doses over 1 gram were required to improve some aspects of cognitive function in older adults ( PLoS One).Ī key area for many is the role of omega-3 fatty acids in the healthy development of a fetus during pregnancy.Ī study from Canada, for example, reported that an increased intake of the omega-3 DHA during pregnancy could produce improved motor function in the offspring in later life ( The Journal of Pediatrics). China: Probiotic supplements in e-commerce.Digestion and immunity probiotic supplements in e-commerce.Explained: The US e-commerce probiotic supplements market.Probiotic supplements: Global e-commerce 2018-2020, forecast for 2021.The gut-brain axis: Psychobiotic opportunity in 25 countries.
0 kommentar(er)
